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Protagonist Therapeutics, Inc.

PTGX· NASDAQ
$143.70+0.60%
2026-09-17

Financials

Valuation Metrics

Protagonist Therapeutics, Inc.'s Market Cap is $9.24B. At end of 2025 it was $5.55B. Ranked #971 of 3,121 in US market (top 31%), #316 of 1,463 on NASDAQ (top 22%), #49 of 266 in Pharmaceuticals, Biotechnology & Life Sciences (top 18%) by Market Cap.

Investment Metrics(as of 2026-09-18)

MetricValue
Size
Market Cap$9.24B
Revenue$282M
Net Income$83M
Total Assets$886M
Net Assets$842M
Employees132
Value
P/E111.47x
P/B10.98x
PEG1.88x
P/S32.77x
EV/EBITDA103.30x
FCF Yield1.43%
Profitability
ROE9.85%
ROA9.36%
Op. Margin20.69%
Revenue Growth34.81%
Earnings Growth59.32%
Financial Health
Debt Ratio5.23%
Total Debt$9M
FCF$132M
Cash$420M
Current Ratio21.71x
Net Debt/EBITDA-4.81x
Performance
1Y Return142.65%
1M Return-8.67%
From 52W High-10.64%
1Y MDD-16.38%
Trading
Volume548,450 shares
Trading Value$79M
Per Share
EPS$1.29
BPS$13.09

Company Info

CEO Dr. Dinesh V. Patel Ph.D.
Employees 132
HQ Newark, United States

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.