Ionis Pharmaceuticals, Inc.

IONS· NASDAQ· Health Care· Pharmaceuticals, Biotechnology & Life Sciences

$54.49+5.25%

2026-08-03

Financials

Valuation Metrics

Ionis Pharmaceuticals, Inc.'s Market Cap is $9.01B. At end of 2025 it was $12.82B. Ranked #1009 of 3,112 in US market (top 32%), #326 of 1,445 on NASDAQ (top 23%), #50 of 269 in Pharmaceuticals, Biotechnology & Life Sciences (top 19%) by Market Cap.

Investment Metrics(as of 2026-08-03)

Metric	Value	Rank
Size
Market Cap	$9.01B	US#1,009/3,112 Sec#50/269
Revenue	$874M	US#2,015/3,112 Sec#59/269
Net Income	$-565M	US—/3,112 Sec—/269
Total Assets	$2.99B	US#1,798/3,112 Sec#44/269
Net Assets	$440M	US#2,344/3,112 Sec#125/269
Value
P/B	20.48x	US#2,816/3,112 Sec#235/269
P/S	10.31x	US#2,671/3,112 Sec#123/269
EV/EBITDA	2.16x	US#22/3,112 Sec#4/269
FCF Yield	-6.21%	US—/3,112 Sec—/269
Profitability
ROE	-128.44%	US#2,880/3,112 Sec#228/269
ROA	-18.86%	US#2,763/3,112 Sec#121/269
Op. Margin	-68.08%	US#2,787/3,112 Sec#115/269
Revenue Growth	-40.73%	US#2,859/3,112 Sec#160/269
Earnings Growth	-192.79%	US#2,224/3,112 Sec#80/269
Financial Health
Debt Ratio	581.14%	US#2,435/3,112 Sec#235/269
Total Debt	$2.42B	US#1,029/3,112 Sec#29/269
FCF	$-559M	US#2,843/3,112 Sec#262/269
Cash	$2.06B	US#417/3,112 Sec#20/269
Current Ratio	7.88x	US#306/3,112 Sec#99/269
Net Debt/EBITDA	0.08x	US#676/3,112 Sec#37/269
Performance
1Y Return	26.63%	US#1,317/3,112 Sec#153/269
1M Return	-33.39%	US#3,082/3,112 Sec#261/269
From 52W High	-37.18%	US#2,440/3,112 Sec#188/269
1Y MDD	-40.15%	US#1,954/3,112 Sec#144/269
Trading
Volume	3,175,267 shares	US#597/3,112 Sec#49/269
Trading Value	$171M	US#590/3,112 Sec#35/269
Per Share
EPS	$-2.35	US—/3,112 Sec—/269
BPS	$3.02	US#2,413/3,112 Sec#158/269